Overview |
bsm-61431r-hrp-100ul |
SMC3 Recombinant Monoclonal Antibody, HRP Conjugated |
WB, IHC-P, IHC-F |
Human, Mouse, Rat |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human SMC3 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
9126 |
Q9UQE7 |
Nucleus |
SMC protein 3; Bamacan; SMC3; BAM; BMH; CSPG6; SMC3L1. |
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |