| Overview |
| bsm-61416r-bf750-100ul |
| TERF1 Recombinant Monoclonal Antibody, AbBy Fluor® 750 Conjugated |
| WB, IF(ICC) |
| Human, Mouse |
| Specifications |
| AbBy Fluor® 750 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TERF1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7013 |
| P54274 |
| Cytoplasm, Nucleus |
| TERF1; PIN2; TRBF1; TRF1. |
| Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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