Overview |
bsm-61416r-100ul |
TERF1 Recombinant Monoclonal Antibody |
WB, IF(ICC) |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human TERF1 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
7013 |
P54274 |
Cytoplasm, Nucleus |
TERF1; PIN2; TRBF1; TRF1. |
Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |