| Overview |
| bsm-61402r-bf555-100ul |
| ASPP2 Recombinant Monoclonal Antibody, AbBy Fluor® 555 Conjugated |
| WB, IF(ICC) |
| Human |
| Specifications |
| AbBy Fluor® 555 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TP53BP2 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7159 |
| Q13625 |
| Nucleus |
| 53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2. |
| Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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