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PARK7/DJ1 Recombinant Monoclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F
  • IP

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61297r-biotin-100ul
Product Name PARK7/DJ1 Recombinant Monoclonal Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F, IP
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PARK7
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 11315
Swiss Prot Q99497
Subcellular location Nucleus, Cell membrane
Synonyms Protein DJ-1; SP22; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7; PARK7.
Background Multifunctional protein with controversial molecular function which plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease.It is involved in neuroprotective mechanisms like the stabilization of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IP 1-2ug