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Cyclooxygenase 1 Recombinant Monoclonal Antibody, APC-Cy5.5 Conjugated

Applications

  • WB
  • FCM
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61288r-apc-cy55-100ul
Product Name Cyclooxygenase 1 Recombinant Monoclonal Antibody, APC-Cy5.5 Conjugated
Applications WB, FCM, IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation APC-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human COX 1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5742
Swiss Prot P23219
Subcellular location Cytoplasm, Cell membrane
Synonyms COX-1; COX1; COX3; Cyclooxygenase-1; PCOX1; PGG/HS; PGH synthase 1; PGH1; PGHS1; PHS1; Prostaglandin G/H synthase 1; Prostaglandin H2 synthase 1; PTGHS; PTGS1.
Background Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200