| Overview |
| bsm-61273r-cy5-100ul |
| ASC/TMS1 Recombinant Monoclonal Antibody, Cy5 Conjugated |
| WB, FCM, IF(ICC) |
| Human |
| Specifications |
| Cy5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ASC |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 29108 |
| Q9ULZ3 |
| Cytoplasm, Nucleus |
| PYCARD; ASC; CARD5; TMS; TMS-1; TMS1. |
| Functions as a key mediator in apoptosis and inflammation.Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner.Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IF(ICC) |
1:50-200 |
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