| Overview |
| bsm-61230r-100ul |
| HTRA2 Monoclonal Antibody |
| WB, IHC-P, IHC-F, IP, IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HTRA2 |
| Monoclonal |
| Recombinant |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 27429 |
| O43464 |
| Cytoplasm, Cell membrane |
| HTRA2; HtrA-like serine protease; OMI; PARK13; Protease; PRSS25; Serine protease 25; HtrA serine peptidase 2; Serine proteinase OMI. |
| Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. |
| Application Dilution |
| WB |
:1:1000-1:2000 |
| IHC-P |
IHC-P:1:100-1:200 |
| IHC-F |
IHC-F:1:100-1:200 |
| IP |
IP:1:20-1:50 |
| IF |
IF:1:100-1:200 |
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