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HTRA2 Recombinant Antibody

Applications

  • WB
  • IHC-P
  • IHC-F
  • IP
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61230r-100ul
Product Name HTRA2 Recombinant Antibody
Applications WB, IHC-P, IHC-F, IP, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HTRA2
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 27429
Swiss Prot O43464
Subcellular location Cytoplasm, Cell membrane
Synonyms HTRA2; HtrA-like serine protease; OMI; PARK13; Protease; PRSS25; Serine protease 25; HtrA serine peptidase 2; Serine proteinase OMI.
Background Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IP 1-2ug
IF