| Overview |
| bsm-61224r-cy3-100ul |
| Lamin B Receptor Recombinant Monoclonal Antibody, Cy3 Conjugated |
| WB, IF(ICC) |
| Human, Rat |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Lamin B Receptor |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3930 |
| Q14739 |
| Cytoplasm, Nucleus, Cell membrane |
| PHA; LMN2R; TDRD18; DHCR14B; LBR. |
| Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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