Overview |
bsm-61224r-100ul |
Lamin B Receptor Recombinant Monoclonal Antibody |
WB, IHC-P, IHC-F, IF(ICC), IP, IF |
Human, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human Lamin B Receptor |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
3930 |
Q14739 |
Cytoplasm, Nucleus, Cell membrane |
PHA; LMN2R; TDRD18; DHCR14B; LBR. |
Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF(ICC) |
1:50-200 |
IP |
1-2ug |
IF |
|