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Lamin B Receptor Recombinant Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC-F
  • IF(ICC)
  • IP
  • IF

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-61224r-100ul
Product Name Lamin B Receptor Recombinant Monoclonal Antibody
Applications WB, IHC-P, IHC-F, IF(ICC), IP, IF
Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Lamin B Receptor
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3930
Swiss Prot Q14739
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms PHA; LMN2R; TDRD18; DHCR14B; LBR.
Background Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200
IP 1-2ug
IF