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LIN28B Recombinant Monoclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
Overview
Catalog # bsm-61215r-pe-cy5-100ul
Product Name LIN28B Recombinant Monoclonal Antibody, PE-Cy5 Conjugated
Applications WB, FCM
Reactivity Human
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Lin 28B
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 389421
Swiss Prot Q6ZN17
Subcellular location Cytoplasm, Nucleus
Synonyms CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B.
Background Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA.
Application Dilution
WB 1:300-5000
FCM 1:20-100