Overview |
bsm-61171r-100ul |
PTPN6 Recombinant Antibody |
WB, IHC-P, IHC-F, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human SHP1 |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
5777 |
P29350 |
Nucleus |
70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1. |
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF |
|