| Overview |
| bsm-61139r-cy55-100ul |
| PIK3CA Recombinant Antibody, Cy5.5 Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PI3 kinase p110 beta |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5290 |
| P42336 |
| Cytoplasm |
| PI 3 Kinase catalytic subunit alpha; phosphoinositide-3-kinase catalytic alpha polypeptide; PI3-kinase p110 alpha; PI3K; PI3K p110-alpha; PK3CA; PIK3CA; PtdIns-3-kinase p110. |
| Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. |
| Application Dilution |
| WB |
1:300-5000 |
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