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Phospho-PP2A alpha (Ser307) Recombinant Antibody, Cy5.5 Conjugated

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61107r-cy55-100ul
Product Name Phospho-PP2A alpha (Ser307) Recombinant Antibody, Cy5.5 Conjugated
Applications WB, IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PP2A alpha around the phosphorylation site of S307
Modification Site Ser307
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5515
Swiss Prot P67775
Subcellular location Nucleus
Synonyms eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786.
Background PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200