| Overview |
| bsm-60737R-BF647 |
| CD11b (7D4) Monoclonal Antibody, AbBy Fluor® 647 Conjugated |
| FCM, IF(ICC) |
| Human |
| Human, Mouse |
| Specifications |
| AbBy Fluor® 647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CD11b |
| Monoclonal |
| 7D4 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20¡C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3684 |
| P05555 |
| Antigen CD11b p170; CD11 antigen like family member B; CD11b antigen; CD49d; Cell surface glycoprotein MAC 1 alpha subunit; Cell Surface Glycoprotein MAC1 Alpha Subunit; Complement Component Receptor 3 Alpha; CR 3 alpha chain; CR3 Alpha Chain; CR3A; Integrin Alpha M; integrin alpha M complement component 3 receptor 3 subunit; Leukocyte Adhesion Receptor MO1; MAC 1; MAC1A; MGC117044; MO1A; Neutrophil Adherence Receptor; CD11b/CD18; F730045J24Rik; Ly-40; ITGAM; CR3A;complement receptor type 3; CR3; ITAM_HUMAN. |
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
|
| Application Dilution |
| FCM |
1:20-100 |
| IF(ICC) |
1:50-200 |
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