Overview |
bsm-54651R |
TPPP Monoclonal Antibody |
WB, FCM, IHC-P, IHC |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Synthetic Peptide within C terminal human TPPP. |
Monoclonal |
7D10 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
11076 |
O94811 |
Cytoplasm, Nucleus, Cytoskeleton |
25 kDa brain specific protein antibody, 25 kDa brain-specific protein antibody, Brain specific protein p25 alpha antibody, Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody, OTTHUMP00000161630 antibody, p24 antibody, p25 antibody, p25-alpha antibody, p25alpha antibody, TPPP antibody, TPPP/p25 antibody, TPPP_HUMAN antibody, TPPP1 antibody, Tubulin polymerization promoting protein antibody, Tubulin polymerization-promoting protein antibody |
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IHC |
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