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Phospho-Stat5(Y694) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-54554R
Product Name Phospho-Stat5(Y694) Monoclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein
Modification Site Tyr694
Clonality Monoclonal
Clone # 3H8
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6776
Swiss Prot P42229
Subcellular location Cytoplasm, Nucleus
Synonyms MGF antibody, Signal transducer and activator of transcription 5A antibody, Signal Transducer and Activator of Transcription 5B antibody, STA5A_HUMAN antibody, STAT 5A antibody, STAT 5B antibody, STAT5 antibody, STAT5A antibody, STAT5B antibody, Transcription factor STAT5A antibody, Transcription factor STAT5B antibody
Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC