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IMPDH2 (2H4) Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IF(IHC-P)
  • IF(ICC)
  • IP

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54443R
Product Name IMPDH2 (2H4) Monoclonal Antibody
Applications WB, FCM, IHC-P, IF(IHC-P), IF(ICC), IP
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein within C-terminal human IMPDH2.
Clonality Monoclonal
Clone # 2H4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3615
Swiss Prot P12268
Subcellular location Cytoplasm, Nucleus
Synonyms Inosine-5'-monophosphate dehydrogenase 2; IMPDH-II, IMP dehydrogenase 2; IMPD 2; IMPDH 2; IMPDH2; IMPD2
Background Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP 1-2ug