Overview |
bsm-54230R |
PCK1 (6C1) Monoclonal Antibody |
FCM, IHC-P, IF(IHC-P), IF(ICC) |
Human |
Specifications |
Unconjugated |
Rabbit |
Synthetic peptide within human PCK1 aa 1-50 |
Monoclonal |
6C1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
5105 |
P35558 |
Cytoplasm |
Phosphoenolpyruvate carboxykinase cytosolic [GTP]; phosphoenolpyruvate carboxykinase 1; PEPCK-C; PCK1; PEPCK1. |
Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate. |
Application Dilution |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |
IF(ICC) |
1:50-200 |