Overview |
bsm-54048r-100ul |
GRIN2A Recombinant Antibody |
WB, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human NMDAR1 aa 750-950 |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment. |
Target |
2903 |
Q12879 |
Glutamate receptor ionotropic, NMDA 2AGlutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, GluN2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A |
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |