SFRP1 (2C4) Monoclonal Antibody

$Human kidney cells lysates probed with SFRP1 (2C4) Monoclonal Antibody (bsm-54003R) at 1:500 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Human kidney cells lysates probed with SFRP1 (2C4) Monoclonal Antibody (bsm-54003R) at 1:500 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Applications

Reactivity

Human

Overview
Catalog #	bsm-54003R
Product Name	SFRP1 (2C4) Monoclonal Antibody
Applications	WB
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Human SFRP1 between 1 to 100 amino acids
Clonality	Monoclonal
Clone #	2C4
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	6422
Swiss Prot	Q8N474
Synonyms	Secreted frizzled-related protein 1, Secreted apoptosis-related protein 2, FRP-1, sFRP-1, SARP-2, SFRP1
Background	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Application Dilution
WB	1:300-5000