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4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-52008M
Product Name 4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody
Applications WB
Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Mouse
Source Synthetic peptide derived from human 4E-BP1/2/3 (Thr 45), around 35-55aa.
Modification Site Thr 45
Clonality Monoclonal
Clone # 3G2
Isotype IgG2a
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 19
Swiss Prot O95477
Synonyms ABCA1 phospho S2054; p-ABCA1 phospho S2054; ATP binding cassette transporter A1; ABC 1; ABC Transporter 1; ABC1; ABCA 1; ABCA1; ATP binding Cassette 1; ATP binding cassette sub family A ABC1 member 1; ATP binding cassette sub family A member 1; ATP binding cassette sub-family A member 1; ATP binding Cassette Transporter 1; ATP-binding Cassette 1; ATP-binding Cassette Transporter 1; CERP; Cholesterol Efflux Regulatory Protein; FLJ14958; HDLDT1; Membrane bound; MGC164864; MGC165011; TD; TGD; ABCA1_HUMAN.
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Application Dilution
WB 1:300-5000