| Overview |
| bsm-51128M |
| TLE4 (4C4) Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4. |
| Monoclonal |
| 4C4 |
| IgM |
| 0.5ug/ul |
| Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 7091 |
| Q04727 |
| ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI); Transducin-like enhancer protein 4; Groucho-related protein 4; TLE4; KIAA1261 |
| Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
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