SIGLEC15 (10E10) 0Monoclonal Antibody, Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-43036M-Cy7 |
| Product Name | SIGLEC15 (10E10) 0Monoclonal Antibody, Cy7 Conjugated |
| Applications | WB |
| Reactivity | Human |
| Specifications | |
| Conjugation | Cy7 |
| Host | Mouse |
| Source | Recombinant human SIGLEC15 protein |
| Clonality | Monoclonal |
| Clone # | 10E10 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 284266 |
| Swiss Prot | Q6ZMC9 |
| Subcellular location | Helical, Cell membrane |
| Synonyms | CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15 |
| Background | Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. |
| Application Dilution | |
| WB | |
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