TTR/Prealbumin Monoclonal Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33358M-Biotin |
| Product Name | TTR/Prealbumin Monoclonal Antibody, Biotin Conjugated |
| Applications | IHC-P, IHC-F |
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Mouse |
| Source | Recombinant human TTR Protein |
| Clonality | Monoclonal |
| Clone # | 3.00E+05 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein G. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 7276 |
| Swiss Prot | P02766 |
| Synonyms | Transthyretin; Amyloid polyneuropathy; Amyloidosis I; ATTR; Dysprealbuminemic euthyroidal hyperthyroxinemia; Dystransthyretinemic hyperthyroxinemia; HsT2651; PALB; Prealbumin amyloidosis type I; Senile systemic amyloidosis; TBPA; Transthyretin; TTR; TTR protein; prealbumin; TTHY_HUMAN. |
| Background | This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq] |
| Application Dilution | |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
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