Overview |
bs-9602R-BF680 |
SRF (Ser77) Polyclonal Antibody, AbBy Fluor® 680 Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
AbBy Fluor® 680 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human SRF around the phosphorylation site of Ser77 |
Ser77 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
6722 |
Serum Response Factor SRF phospho S77; SRF phospho Ser77; P-SRF Ser77; c fos serum response element binding factor; Serum Response Factor SRF; c fos serum response element binding transcription factor; ELK3; ERP; MCM 1; MCM-1; MCM1; OTTHUMP00000039820; SAP2; Serum response factor; SRF; SRF serum response factor c fos serum response element binding transcription factor; SRF_HUMAN. |
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |