Overview |
bs-9514R-BF647 |
PI14 Polyclonal Antibody, AbBy Fluor® 647 Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
AbBy Fluor® 647 |
Rabbit |
KLH conjugated synthetic peptide derived from human SERPINI2/PI14 |
151-250/405 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5276 |
MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specic protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine or cysteine proteinase inhibitor clade I neuroserpin member 2; Serine or cysteine proteinase inhibitor clade I pancpin member 2; Serpin I2; Serpin peptidase inhibitor clade I pancpin member 2; TSA2004; SPI2_HUMAN; SERPINI2. |
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |