Overview |
bs-9352R-APC-Cy7 |
Proteasome 20S alpha 3 Antibody, APC-Cy7 Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat, Others |
Specifications |
APC-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 3 |
155-255/255 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5684 |
20S Proteasome 3; HC8; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome prosome macropain subunit alpha type 3; Proteasome alpha 3 subunit; Proteasome component C8; Proteasome subunit alpha type 3; Proteasome subunit alpha type-3; Proteasome subunit C8; PSA3_HUMAN; PSC3; PSMA3. |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |