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RanBP2 Polyclonal Antibody, RBITC Conjugated

Applications

  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
  • Others
Overview
Catalog # bs-9323R-RBITC
Product Name RanBP2 Polyclonal Antibody, RBITC Conjugated
Applications IF(IHC-P)
Reactivity Human, Mouse, Rat, Others
Specifications
Conjugation RBITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RanBP2
Immunogen Range 1151-1350/3220
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5903
Synonyms Nuclear pore complex protein Nup358; Nucleoporin 358; Nucleoporin Nup358; NUP358; P270; RAN binding protein 2; Ran-binding protein 2; RANBP2; RBP2_HUMAN; Transformation related protein 2; TRP 1; TRP 2; TRP1; TRP2; 358 kDa nucleoporin; E3 SUMO-protein ligase RanBP2.
Background The nuclear pore complex protein, Ran-binding protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes. In humans, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q. This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia.
Application Dilution
IF(IHC-P) 1:50-200