Stargazin Antibody

Applications

Reactivity

Predicted Reactivity

Mouse

Overview
Catalog #	bs-70263r-100ul
Product Name	Stargazin Antibody
Applications	WB
Specificity	Specific for endogenous levels of the ~36kDa stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen.
Reactivity	Rat
Predicted Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat Stargazin, conjugated to keyhole limpet hemocyanin (KLH).
Clonality	Polyclonal
Isotype	IgG
Concentration	Lot Dependent
Purification	Antigen Affinity purification from Pooled whole antiserum
Storage Buffer	10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Storage Condition	Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID	12300
Swiss Prot	O88602
Synonyms	AW060990 antibody, B230105C07Rik antibody, B930041E13Rik antibody, Cacng2 antibody, Calcium channel voltage dependent gamma subunit 2 antibody, CaV gamma 2 antibody, CCG2_HUMAN antibody, Ipr328 antibody, MGC123981 antibody, MGC138502 antibody, MGC138504 antibody, Neuronal voltage gated calcium channel gamma 2 subunit antibody, Neuronal voltage-gated calcium channel gamma-2 subunit antibody, Stargazer antibody, stg antibody, TARP gamma-2 antibody, Transmembrane AMPAR regulatory protein gamma-2 antibody, Voltage dependent calcium channel gamma 2 subunit antibody, Voltage-dependent calcium channel gamma-2 subunit antibody, Wag antibody, Waggler antibody
Background	Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr-321- by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002).
Application Dilution
WB	1:300-5000