| Overview |
| bs-70129r-100ul |
| GRIP1 Associated Protein 1 (GRASP1) Antibody |
| WB |
| Specific for endogenous levels of the ~95 kDa GRASP1 protein. |
| Mouse, Rat |
| Human, Dog, Bovine |
| Specifications |
| Unconjugated |
| Rabbit |
| Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GRASP1, conjugated to keyhole limpet hemocyanin (KLH). |
| Polyclonal |
| IgG |
| Lot Dependent |
| Antigen Affinity purification from Pooled whole antiserum |
| 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target |
| 116493 |
| Q9JHZ4 |
| DKFZp434P0630 antibody, DXImx47e antibody, GRAP1_HUMAN antibody, GRASP 1 antibody, GRASP-1 antibody, GRASP1 antibody, GRIP 1 associated protein 1 antibody, GRIP associated protein 1 antibody, GRIP1 associated protein 1 antibody, GRIP1-associated protein 1 antibody, GRIPAP 1 antibody, GRIPAP1 antibody, KIAA1167 antibody, MGC126593 antibody, MGC126595 antibody, MPMGp800B12492Q3 antibody, Sfc10 antibody, TAMALIN antibody |
| PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). |
| Application Dilution |
| WB |
1:300-5000 |
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