New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

GRIP1 Associated Protein 1 (GRASP1) Antibody

Applications

  • WB

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Bovine
Overview
Catalog # bs-70129R
Product Name GRIP1 Associated Protein 1 (GRASP1) Antibody
Applications WB
Specificity Specific for endogenous levels of the ~95 kDa GRASP1 protein.
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Bovine
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GRASP1, conjugated to keyhole limpet hemocyanin (KLH).
Clonality Polyclonal
Isotype IgG
Concentration Lot Dependent
Purification Antigen Affinity purification from Pooled whole antiserum
Storage Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Storage Condition Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID 116493
Swiss Prot Q9JHZ4
Synonyms DKFZp434P0630 antibody, DXImx47e antibody, GRAP1_HUMAN antibody, GRASP 1 antibody, GRASP-1 antibody, GRASP1 antibody, GRIP 1 associated protein 1 antibody, GRIP associated protein 1 antibody, GRIP1 associated protein 1 antibody, GRIP1-associated protein 1 antibody, GRIPAP 1 antibody, GRIPAP1 antibody, KIAA1167 antibody, MGC126593 antibody, MGC126595 antibody, MPMGp800B12492Q3 antibody, Sfc10 antibody, TAMALIN antibody
Background PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
Application Dilution
WB 1:300-5000