Overview |
bs-70124r-100ul |
GluR2/3 Antibody |
WB |
Specific for endogenous levels of the ~100 kDa GluR2/3 protein. |
Rat |
Human, Mouse, Chicken, Zebrafish |
Specifications |
Unconjugated |
Rabbit |
Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GluR2/3, conjugated to keyhole limpet hemocyanin (KLH). |
Polyclonal |
IgG |
Lot Dependent |
Antigen Affinity purification from Pooled whole antiserum |
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
Target |
29627 |
P19491 |
AMPA selective glutamate receptor 2 antibody, AMPA selective glutamate receptor 3 antibody, GluR K2 antibody, GluR K3 antibody, GLURB antibody, GLURC antibody, GLUTAMATE RECEPTOR 2 antibody, GLUTAMATE RECEPTOR 3 antibody, Glutamate receptor ionotropic AMPA 2 antibody, Glutamate receptor ionotropic AMPA 3 antibody, GRIA2 antibody, GRIA3 antibody |
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003;Seidenman et al., 2003;Chung et al., 2003;Yan et al., 2002). |
Application Dilution |
WB |
1:300-5000 |