| Overview |
| bs-6949R-PE-Cy7 |
| Factor B Polyclonal Antibody, PE-Cy7 Conjugated |
| WB |
| Mouse, Rat |
| Specifications |
| PE-Cy7 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment |
| 301-400/764 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 629 |
| P00751 |
| Secreted |
| BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB |
| Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Application Dilution |
| WB |
1:300-5000 |
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