Overview |
bs-6094R-Cy7 |
RIN1 Polyclonal Antibody, Cy7 Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Rat |
Human, Mouse, Cow, Pig |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human RIN1 |
201-300/783 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
9610 |
Cytoplasm, Cell membrane |
Ras and Rab interactor 1; ras inhibitor 1; ras inhibitor; RIN1_HUMAN; Ras inhibitor JC99; ras inhibitor RIN1; Ras interaction/interference protein 1; RIN 1. |
RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer. |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |