Overview |
bs-5925R-Cy7 |
MAS1 Polyclonal Antibody, Cy7 Conjugated |
WB |
Human, Mouse |
Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit, Guinea Pig |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human MAS1 |
51-150/325 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
4142 |
P04201 |
Cell membrane |
MAS; MGRA; Proto-oncogene Mas; MAS1 |
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
Application Dilution |
WB |
1:300-5000 |