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LITAF Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IP
  • IHC

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-55125R
Product Name LITAF Polyclonal Antibody
Applications WB, IHC-P, IP, IHC
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_004853.2).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 9516
Swiss Prot Q99732
Subcellular location Cytoplasm
Synonyms LITAF;PIG7;SIMPLE;TP53I7
Background Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IP 1-2ug
IHC