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FUS Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IHC
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-55081R
Product Name FUS Polyclonal Antibody
Applications WB, IHC-P, IF(ICC), IHC, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 2521
Swiss Prot P35637
Subcellular location Nucleus
Synonyms FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;TLS
Background This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC
IF