CDYL Polyclonal Antibody

Overview
Catalog #	bs-53086R
Product Name	CDYL Polyclonal Antibody
Applications	ELISA
Reactivity	Human, Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Polyclonal antibody raised in rabbit against human CDYL (chromodomain protein, Y-like) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein
Clonality	Polyclonal
Isotype	Not Determined
Concentration	Not Determined
Purification	Whole antiserum from rabbit containing 0.05% azide
Storage Buffer	Serum with 0.05% sodium azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	9425
Swiss Prot	Q9Y232
Synonyms	CDYL1, Chromodomain Y-like protein, CDYL
Background	Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.
Application Dilution
ELISA	1:500-1000