| Overview |
| bs-53078R |
| Jarid1c Polyclonal Antibody |
| ELISA |
| Human, Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against mouse Jarid1c (jumonji, AT rich interactive domain 1C), using 3 KLH-conjugated synthetic peptides containing sequences from the inner part of the protein |
| Polyclonal |
| Not Determined |
| Not Determined |
| Whole antiserum from rabbit containing 0.05% azide |
| Serum with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 8242 |
| P41229 |
| KDM5C, MRXJ, MRXSJ, SMCX, XE169 |
| Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. |
| Application Dilution |
| ELISA |
1:500-1000 |
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