Overview |
bs-53053R |
H3K27me3 (Ser28) Polyclonal Antibody |
WB, ELISA, IP, IF, dot-blot, ChIP-seq |
Human |
Specifications |
Unconjugated |
Rabbit |
Polyclonal antibody raised in rabbit against histone H3 containing the trimethylated lysine 27 and the phosphorylated serine 28 (H3K27me3S28p), using a KLH-conjugated synthetic peptide |
Ser28 |
Polyclonal |
Not Determined |
Not Determined |
Whole antiserum from rabbit containing 0.05% azide |
Serum with 0.05% sodium azide. |
Store at -20°C for 12 months. |
Target |
8350 |
P68431 |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IP |
1-2ug |
IF |
|
dot-blot |
|
ChIP-seq |
|