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H3K27me3 (Ser28) Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IP
  • IF
  • dot-blot
  • ChIP-seq

Reactivity

  • Human
Overview
Catalog # bs-53053R
Product Name H3K27me3 (Ser28) Polyclonal Antibody
Applications WB, ELISA, IP, IF, dot-blot, ChIP-seq
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Polyclonal antibody raised in rabbit against histone H3 containing the trimethylated lysine 27 and the phosphorylated serine 28 (H3K27me3S28p), using a KLH-conjugated synthetic peptide
Modification Site Ser28
Clonality Polyclonal
Isotype Not Determined
Concentration Not Determined
Purification Whole antiserum from rabbit containing 0.05% azide
Storage Buffer Serum with 0.05% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 8350
Swiss Prot P68431
Background Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IP 1-2ug
IF
dot-blot
ChIP-seq