| Overview |
| bs-51077R |
| ZBTB4 Polyclonal Antibody |
| WB, ELISA |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against human ZBTB4 (zinc finger and BTB domain containing 4), using four different KLH-conjugated synthetic peptides |
| Polyclonal |
| Not determined |
| Not Determined |
| Whole antiserum from rabbit containing 0.05% azide |
| Serum with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 57659 |
| Q9P1Z0 |
| Zinc finger and BTB domain-containing protein 4, ZBTB4, |
| Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
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