| Overview |
| bs-51067R |
| Jarid1b Polyclonal Antibody |
| WB, ELISA |
| Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against mouse Jarid1b, using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein |
| Polyclonal |
| Not determined |
| Not Determined |
| Whole antiserum from rabbit containing 0.05% azide |
| Serum with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 10765 |
| Q9UGL1 |
| CT31, PLU1, PUT1, RBBP2H1, RBP2-like |
| Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
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