Overview |
bs-4857R-BF680 |
Hepatitis C Virus NS4B Antibody, AbBy Fluor® 680 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Virus |
Specifications |
AbBy Fluor® 680 |
Rabbit |
KLH conjugated synthetic peptide derived from Hepatitis C Virus NS4B |
1712-1820/3010 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
P26663 |
Cytoplasm, Cell membrane |
HCV; HCV NS4B; Non structural protein 4B; NS4B; p27. |
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. NS4B induces a specific membrane alteration that serves as a scaffold for the virus replication complex. This membrane alteration gives rise to the so-called ER-derived membranous web that contains the replication complex. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |