Overview |
bs-4720R-PE |
GDF9 Polyclonal Antibody, PE Conjugated |
WB, FCM |
Human, Mouse, Rat |
Dog, Cow, Sheep, Pig, Horse, Chicken |
Specifications |
PE |
Rabbit |
KLH conjugated synthetic peptide derived from human GDF9 |
301-400/454 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2661 |
O60383 |
Secreted |
Growth/differentiation factor 9; GDF-9; GDF9 |
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |