| Overview |
| bs-4214R-Cy3 |
| GIRK2 Polyclonal Antibody, Cy3 Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GIRK2 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3763 |
| Cytoplasm |
| inwardly rectying subfamily J member 6; Kir3.2; BIR1; G protein activated inward rectier potassium channel 2; G protein-activated inward rectier potassium channel 2; GIRK-2; Inward rectier K+ channel Kir3.2; IRK6_HUMAN; KATP-2; Kcnj6; Kcnj7; Potassium channel; Potassium channel inwardly rectying subfamily J member 6. |
| This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
| Application Dilution |
| WB |
1:500-2000 |
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