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RSV N Polyclonal Antibody

Applications

  • WB

Reactivity

  • respiratory syncytial virus
Overview
Catalog # bs-42024r-100ul
Product Name RSV N Polyclonal Antibody
Applications WB
Reactivity respiratory syncytial virus
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant HRSVA Nucleoprotein protein
Immunogen Range 1-391/391
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Target
Subcellular location Secreted, Cell membrane, Extracellular matrix
Synonyms Respiratory syncytial virus nucleoprotein; N; NCAP_HRSVA; Nucleoprotein; Protein N; Nucleocapsid protein.
Background Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities.
Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors.
Application Dilution
WB =1:500-2000