Overview |
bs-3651R-Biotin |
JAM1 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA |
Rat |
Human, Mouse, Dog, Cow, Pig |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1 |
51-150/299 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
50848 |
Q9Y624 |
Cell membrane |
JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; F11R; UNQ264/PRO301 |
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |