| Overview |
| bs-3576R-HRP |
| HB-EGF Polyclonal Antibody, HRP Conjugated |
| ELISA, IHC-P |
| Human, Mouse, Rat |
| Dog, Cow, Pig, Horse, Chicken, Rabbit |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HB-EGF/DTSF |
| 51-150/208 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1839 |
| Q99075 |
| Secreted, Cell membrane |
| DTR; DTS; DTSF; HEGFL; Proheparin-binding EGF-like growth factor; HBEGF |
| Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
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