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Tyk2(Tyr1054 + Tyr1055) Antibody, Cy3 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
Overview
Catalog # bs-3437R-Cy3
Product Name Tyk2(Tyr1054 + Tyr1055) Antibody, Cy3 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055
Modification Site Tyr1054 + Tyr1055
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7297
Subcellular location Cytoplasm, Nucleus
Synonyms TYK2Tyr1054/1055; Tyk2phospho Y1054/1055; TYK2 phospho Tyr1054/1055; p-TYK2 Tyr1054/1055; JTK 1; JTK1; TYK 2; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Protein Tyrosine Kinase 2; Tyrosine kinase 2; TYK2_HUMAN; Non-receptor tyrosine-protein kinase TYK2.
Background This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200