| Overview |
| bs-3270R-Biotin |
| MEK1/2(Ser218 + Ser222) Antibody, Biotin Conjugated |
| WB, ELISA |
| These phosphorylation sites are homologous to Ser222 + Ser226 in MEK2 and are the same across the listed species. |
| Human |
| Mouse, Rat, Dog, Cow, Pig, Chicken, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222 |
| Ser218 + Ser222 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 56045605 |
| Cytoplasm, Nucleus, Cell membrane |
| MAP2K1phospho S218/S222; Dual specicity mitogen activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAP/Erk kinase 1; Map2K1; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MKK1; PRKMK 1; PRKMK1;Protein kinase mitogen activated kinase 1 MAP kinase kinase 1; Protein kinase mitogen activated kinase 1; Protein kinase mitogen activated, kinase 1. |
| The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
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